I noticed people use the term "F*CK MY LIFE" or simply "FML" so much lately and remembered that it became popular from this scene (above) in Superbad.
Definition from Urban Dictionary for those of you who have been living under a rock:
It's when life gets really hard, and all you want to say is "f*ck my life" or when one is in a bad situation and needs to fill that agravated sigh in with a word, FML.
Broseph: Yo i got a 85 on the test, how'd you do?
Broski: I failed... FML.
Today, it was easter and I thought it might be fun to look for eggs with my little brother. My parents told me to take the ones in the higher places that my brother couldn't reach. All of his eggs were filled with candy or money. Each one of mine had a note saying 'maybe when you lose weight'. FML